Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome
Healthcare providers prescribe them to manage and treat various bacterial infections
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pyogenes resistance to β-lactams and non-β-lactams, such as macrolides and tetracycline-class
The traditional SPE procedure was replaced by an acidity-regulated extraction-partition-concentration protocol to improve sample preparation efficiency
Remarkably, the context-specificity of the macrolide action is not based on the inability of some nascent polypeptides to bypass the antibiotic in the NPET
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5 Macrolides are typically used as 2nd-line alternatives to penicillin antibiotics when a patient has an allergy
The tested antibiotics were: Azithromycin, a common macrolide broad-spectrum antibiotic derived from erythromycin; doxycycline, a tetracycline derivative also used as broad-spectrum antibiotic; tigecycline, a new generation tetracycline also called glycylcyclines with a similar mechanism of action and pyrvinium pamoate which is a
(2001) Tetracycline antibiotics: mode of action, applications, molecular biology and epidemiology of bacterial resistance
Sulfonamides were detected at the
, tetracyclines, macrolides, and cephalosporins) and even different antibiotics within the same class (i
As expected, fluoroquinolone and tetracycline regimens were shown to be more effective than macrolide regimens in patients infected by macrolide-resistant M
Since antibiotic interaction with target molecule is generally quite specific, minor alteration of the target molecule can have important effect on antibiotic binding
They are active against many-penicillin-resistant staphylococci, but some are now also resistant to the macrolides
Gastrointestinal side effects have included anogenital lesions with monilial overgrowth, anorexia, black hairy tongue, dysphagia, enamel hypoplasia, enterocolitis, epigastric distress, diarrhea, glossitis, nausea, permanent tooth discoloration, and vomiting
Doxycycline is a tetracycline antibiotic that is used to treat susceptible bacterial infections of both gram-positive and gram-negative organisms, as well as infections caused by Mycoplasma, Chlamydophilia, and Rickettsia organisms
The macrolide antibiotic, roxithromycin suppresses IFN-γ-mediated immunological functions of cultured normal human keratinocytes
Macrolide antibiotics (MAs), as a typical emerging pollutant, are widely detected in environmental media
Troleandomycin: For the treatment of bacterial infection