What is this medication? CHLORPROMAZINE (klor PROE ma zeen) treats several kinds of mental health conditions, such as schizophrenia and bipolar disorder
Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies
Oral: 10 to 25 mg orally every 4 to 6 hours as needed for nausea/vomiting
It is used in the treatment of persons with psychotic disorders
On the other hand, a new molecule called imipramine was synthesized in
Total daily doses should be increased in 20 to 50mg increments every 3 or 4 days until symptoms are controlled
Chlorpromazine was synthesized on December 11, 1951 by Paul Charpentier, in the laboratories of Rhône-Poulenc, a French pharmaceutical company, and released for clinical investigation in May 1952 as a possible potentiator of general anesthesia ( Charpentier et al 1952 )
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In a rat model of hypoxia, Chlorpromazine HCl reduced irreversible loss of synaptic transmission in brain tissues
Antipsychotic medications
Find information on Chlorpromazine (Thorazine) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more
Chlorpromazine is low‐cost and widely available
These may lead to falling, which can cause broken bones or other health problems
This medication is used to treat certain mental/mood disorders (such as schizophrenia, psychotic disorders, manic phase of bipolar disorder, severe behavioral problems in children)
Chemical name: 2-Chloro-10- [3- (dimethylamino)propyl]-phenothiazine monohydrochloride
Includes: indications, dosage, adverse reactions and pharmacology
An unsafe heartbeat that is not normal (long QT on ECG) has happened with this medicine (chlorpromazine tablets)
When chlorpromazine is used to relieve nervousness before surgery, it is usually taken 2-3 hours before surgery
Medicine to reverse the effects of the drug and treat symptoms; Outlook (Prognosis) Chlorpromazine is fairly safe
Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS