The name "cyanocobalamin" is derived from including a cyanide group within the molecule
The monomer of G6PD is composed of 515 amino acids with a molecular weight of about 59 kDa (Cappellini and Fiorelli, 2008)
Here, we provide an overview of G6PD as a very important pharmacogene, and detail genetic variants and haplotypes
So, IHD can also be thought of as (multiple bonds + rings) or ( π + r )
Chloramphenicol is a broad spectrum antibiotic introduced into clinical practice in 1948, but which was subsequently shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available
Chloramphenicol should not be used topically because small amounts may be absorbed and, rarely, cause aplastic anemia
May cause: dose-related haematological toxicity (bone marrow depression, anaemia, leucopenia, thrombocytopenia), allergic reactions
This will give chloroethane an IHD of zero same as ethane
Step 1: Determine the formula for the saturated acyclic hydrocarbon containing the same number of carbon atoms as the unknown substance
The deficiency is an X-linked hereditary genetic These drugs can interact with hemoglobin and oxygen, leading to the intracellular formation of hydrogen peroxide (H 2 O 2) and The survival of glucose-6-phosphate dehydrogenase–deficient erythrocytes in patients with typhoid fever on chloramphenicol therapy
The molecule possesses two asymmetric carbon atoms (marked with asterisk in the figure)
In this exercise students briefly review concepts relating to chemical bonds prior to being introduced to the concept of the Index of Hydrogen Deficiency (IHD)